Morphological Adaptation

Investigating Morphological Adaptation in Naturally Evolving Populations of Stickleback Fish

Sticklebacks from different ecological backgrounds (limnetic, in deep and large lakes vs. benthic, in smaller and shallow lakes) were reintroduced into lakes to observe evolutionary patterns. The FITNESS project tracks these fish populations over time to test if phenotypic and genotypic changes can be predicted as each group adapts to their new surroundings. This project leverages machine learning (ML) and µCT imaging to develop scalable methods for analyzing fish anatomy.

Ongoing research directions

Fish photographs are taken in the field, and later scanned using µCT to visualize internal anatomical structures, particularly those related to feeding (e.g., branchial arches). ML models and pipelines (based around platforms like Biomedisa and ML-Morph) assist in segmentation and landmarking these data. Comparative analysis using both 2D digital photographs and 3D µCT scans to understand morphological variation. The integration of sex data and lake habitat info enables multifactorial analysis.
The research provides insights into evolutionary predictability and refines data pipelines for high-throughput morphometric analyses, making large-scale evolutionary studies feasible using geometric morphometric techniques.

The project promotes collaboration within the University of Bern and supports public science engagement (e.g., Pint of Science, Nacht der Forschung) and is also financially supported by the Burgergemeinde Bern.

Selected and cited publications 

1. Roesti, M. et al. Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation. Cold Spring Harb Perspect Biol a041456 (2024) doi:10.1101/cshperspect.a041456. 

2. Hendry, A. P. et al. Designing eco-evolutionary experiments for restoration projects: Opportunities and constraints revealed during stickleback introductions. Ecology and Evolution 14, e11503 (2024).